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Peripheral Fat Breakdown Undermined By Bad Cholesterol

The so called bad cholesterol (LDL) inhibits the breakdown of fat in cells of peripheral deposits, according to a study from the Swedish medical university Karolinska Institutet. The discovery reveals a novel function of LDL as a regulator of fat turnover besides its well-established detrimental effects in promoting atherosclerosis. The study, which is a collaboration of two research groups at Karolinska Institutet, is published in the open-access journal PLoS ONE.[more]

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Published: Thu, 20 Nov 2008 03:00:00 PST
Metabolex Announces Positive Results From Phase 2 Clinical Trial Of MBX-8025

Metabolex, Inc., a biopharmaceutical company focused on the discovery and development of proprietary new medicines for the treatment of metabolic diseases, announced positive results from a Phase 2 clinical trial of MBX-8025. A summary of the results was presented at the World Congress on Controversies to Consensus in Diabetes, Obesity and Hypertension (CODHy) on November 1, 2008. MBX-8025 is an oral drug candidate that is being evaluated for the treatment of dyslipidemia.[more]

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Published: Wed, 19 Nov 2008 00:00:00 PST
Soy Protein's Ability To Lower Cholesterol Confirmed, Possible Mechanism Of Action Described

Solae, a leader in soy protein innovation and technology, unveiled a new study today at the 8th International Symposium on the Role of Soy in Health Promotion and Chronic Disease Prevention and Treatment. A new meta-analysis confirms that soy protein consumption can lead to a meaningful and significant reduction in blood cholesterol levels.[more]

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Published: Mon, 17 Nov 2008 08:00:00 PST
Colesevelam HCl Lowered LDL Cholesterol In Pediatric Patients With Heterozygous Familial Hypercholesterolemia

Daiichi Sankyo, Inc. (DSI), announced today that results from the pivotal study supporting the use of colesevelam HCl in pediatric patients with heterozygous familial hypercholesterolemia (heFH), were presented for the first time at the American Heart Association's (AHA) Annual Scientific Sessions 2008.[more]

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Published: Mon, 17 Nov 2008 05:00:00 PST
The Influence Of Statin Medications On Prostate-specific Antigen Levels

UroToday.com - According to a report by Dr. Robert J. Hamilton and associates that appears in the November 5, 2008 issue of the Journal of the National Cancer Institute, statin use lowers PSA levels, and as a result may confound the detection of prostate cancer (CaP) in these patients. Statins are lipid-lowering agents in widespread use in the US. Several reports suggest that men on statins have a reduction in the risk of advanced CaP that ranges from 25% to 75%.[more]

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Published: Sat, 15 Nov 2008 01:00:00 PST
GP Survey Shows Concerns Over Tolerability Of Higher Dose Statins

According to the results of a new survey of 500 GPs across the UK, many GPs have concerns about the tolerability profile of higher doses of statins that are significant enough to affect their prescribing decisions.[more]

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Published: Fri, 14 Nov 2008 04:00:00 PST
Damage Inflicted During Cardiac Attacks More Widespread Than Previously Thought, MSU Researchers Find

Cholesterol crystals released in the bloodstream during a cardiac attack or stroke can damage artery linings much further away from the site of the attack, leaving survivors at greater risk than previously thought.[more]

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Published: Wed, 12 Nov 2008 07:00:00 PST
Health Risks For Large, Retired Athletes May Be Lowered By Staying Active

Study highlights: Retired NFL players have fewer heart disease risk factors overall, but higher cholesterol and glucose levels. Physical activity may have prevented the development of higher rates of diabetes or greater amounts of atherosclerosis. Since today's players are 50 percent larger than 25 years ago, further study is needed on whether current players are at greater risk for cardiovascular events or death, researchers said.[more]

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Published: Wed, 12 Nov 2008 04:00:00 PST
Statin Reduces Heart Attack, Stroke Rates In Patients With Normal Cholesterol But Elevated C-Reactive Protein

New data from the landmark ATHENA trial showed that dronedarone significantly reduced the incidence and total duration of hospital stays among patients with atrial fibrillation/atrial flutter (AF/AFL). This post-hoc analysis was presented at the 2008 American Heart Association Scientific Sessions in New Orleans, Louisiana. In this new analysis, dronedarone significantly reduced the total number of hospital days by 28 percent (p[more]

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Published: Wed, 12 Nov 2008 00:00:00 PST
Colesevelam HCl Lowered LDL Cholesterol In Pediatric Patients With Heterozygous Familial Hypercholesterolemia

Daiichi Sankyo, Inc. (DSI), announced that results from the pivotal study supporting the use of colesevelam HCl in pediatric patients with heterozygous familial hypercholesterolemia (heFH), were presented for the first time at the American Heart Association's (AHA) Annual Scientific Sessions 2008.[more]

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Published: Wed, 12 Nov 2008 00:00:00 PST
 
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